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For Medical Professionals

Compounding & Compatibility

Disclaimer: This data is provided for informational purposes only, representing the results of a study of product stability with various active pharmaceutical ingredients. It does not serve, and cannot be construed, as representation of guarantee of product performance. In all cases the pharmacist is advised to consult recognized pharmaceutical compendia and other sources for product formulation, characteristics and methods used, including stability. Pharmaceutical Specialties, Inc. makes no warranties or presentations with regard to the appropriateness of this product in any compounded formulation and is solely at the discretion and liability of the pharmacist and practitioner relationship.

Key:
● Formulation is compatible
x Formulation is incompatible
+ Stability data is available
○ Formulation is not studied

Active(s) and Concentration

Vanicream Cream

L-Ascorbic acid (5%), (20%)

x

Benzoyl peroxide (1.5%), Erythromycin (3%)

Clindamycin (2%), Tretinoin (0.015%)

Coal Tar (LCD) (10%)

Cromolyn sodium (4%)

+

Crude coal tar (2%)

Dehydroepiandrosterone (0.1%), (5%)

+

Dexamethasone sodium phosphate (0.4%)

+

Erythromycin (2%)

Estradiol (0.6%)

+

Estradiol (0.01%), Vitamin E Succinate (2%)

+

Estradiol (0.01%), Estriol (0.01%), Estrone (0.01%), Progesterone (0.1%)

+

Estradiol (1%), Estriol (1%), Estrone (1%), Progesterone (25%)

+

Glycolic acid (5%), (20%)

Hydrocortisone (2%)

Hydroquinone (4%)

x

Ichthammol (3%)

Ketoprofen (10%)

+

Lactic acid (12%)

Menthol (4%)

Menthol (0.1%), Phenol (0.1%)

Niacinamide (5%)

Oil-in-water bases

Oxybenzone (6%)

Phenol (above 1%)

x

Progesterone (20%)

+

Salicylic acid (5%)

Salicylic acid (2%), Sulfur (2%)

Salicylic acid (10%), Urea (20%)

Starch (15%), Zinc oxide (10%)

Testosterone (1%), (2%)

+

Tretinoin (0.05%)

Triamcinolone acetonide (0.025%), (0.5%)

+

Urea (20%)

Water